Cremophor EL

Research use only, not for human use.

Cremophor EL is a nonionic surfactant. cremophor EL inhibits cellular metabolism and suppresses UGT1A1-mediated rhodopsin glucuronidation.

Cremophor EL, a polyoxyethylene castor oil derivative, is a nonionic surfactant. Cremophor EL is widely employed to improve dissolution and delivery of agents.

Cremophor EL is a widely used excipient. In the first 10 h, Cremophor EL at 5 mg/mL increases the impedance, then decreases it, and after 20 h of treatment, epithelial cell death is detected. Cremophor EL decreases cell viability and increases cell toxicity more than RH40. Both epithelial viability and monolayer integrity are seriously impaired at 10 to 50 mg/mL concentrations of Cremophor EL at 24-h treatment. Cremophor EL also enhances cell detachment.

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Others

Other Targets

UGT

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61791-12-6

172.01

C4H7Cl2NO2

>98% (HPLC)

In Vitro:?Ethanol : 50 mg/mL (Ultrasonic)H2O : 25 mg/mL (Ultrasonic)

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(-20℃)

With Ice Pack

≥ 2 years